How to Prevent Muscle Loss While Taking GLP-1 Medications
One of the most important risks of GLP-1 medications is muscle loss. Studies suggest 25 to 40 percent of weight lost may come from lean muscle mass.
Why GLP-1 Medications Cause Muscle Loss
When the body is in a caloric deficit it breaks down both fat and muscle for energy.
Signs You May Be Losing Muscle
- Feeling weaker than usual during everyday activities
- Decreased exercise performance or endurance
- Fatigue that goes beyond normal GLP-1 side effects
Prioritize Protein Intake
Most weight loss physicians recommend 1.2 to 1.6 grams of protein per kilogram of body weight per day.
Resistance Training
Aim for at least two to three resistance training sessions per week.
GLP-1 and Hair Loss
Another common side effect is hair loss known as telogen effluvium beginning 2 to 3 months after starting treatment.
Consider Supportive Treatments
Options include creatine monohydrate, leucine-rich whey protein, NAD+ for cellular energy support, and Sermorelin.
Find a medical weight loss clinic near you using our directory.
Support Your Health During GLP-1 Treatment
These providers offer GLP-1 medications and supportive treatments to help you preserve muscle and manage side effects:
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Frequently Asked Questions
Does Ozempic cause muscle loss?
Studies suggest that 25 to 40 percent of weight lost on GLP-1 medications like Ozempic can come from lean muscle mass if protein intake and resistance training are not prioritized during treatment.
How much protein should I eat on GLP-1 medication?
Most weight loss physicians recommend 1.2 to 1.6 grams of protein per kilogram of body weight per day to help preserve muscle mass during GLP-1 treatment.
Can exercise prevent muscle loss on Ozempic?
Yes, resistance training two to three times per week is one of the most effective ways to signal your body to preserve muscle tissue during GLP-1 weight loss.
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